Based on the latest Bureau of Labor Statistics OEWS data — updated August 12, 2026.
| South Carolina | National | Difference | |
|---|---|---|---|
| Median annual salary | $122,490 | $140,258 | -13% |
| Median hourly wage | $58.89 | $67.43 | -13% |
Adjusted for local price levels (100 = national average), the cost-adjusted median is $130,726.
| City | Median | Entry Level | Experienced | Cost of Living |
|---|---|---|---|---|
| City-level data coming soon. | ||||
The median annual salary for a Physician Assistant in South Carolina is $122,490, or about $58.89 per hour, according to BLS OEWS data.
The national median for Physician Assistants is $140,258. South Carolina is -13% below the national median.
Entry-level physician assistants in South Carolina typically earn from varies by experience depending on the city and employer.
With 2,250 physician assistant jobs on record and a median salary of $122,490, South Carolina offers competitive pay compared to the rest of the country.