Based on the latest Bureau of Labor Statistics OEWS data — updated August 12, 2026.
| Missouri | National | Difference | |
|---|---|---|---|
| Median annual salary | $129,930 | $135,791 | -4% |
| Median hourly wage | $62.47 | $65.28 | -4% |
Adjusted for local price levels (100 = national average), the cost-adjusted median is $143,095.
| City | Median | Entry Level | Experienced | Cost of Living |
|---|---|---|---|---|
| Kansas City | $122,066 | $95,000 | $147,250 | 91 |
The median annual salary for a Nurse Practitioner in Missouri is $129,930, or about $62.47 per hour, according to BLS OEWS data.
The national median for Nurse Practitioners is $135,791. Missouri is -4% below the national median.
Entry-level nurse practitioners in Missouri typically earn from $95,000 depending on the city and employer.
With 7,710 nurse practitioner jobs on record and a median salary of $129,930, Missouri offers competitive pay compared to the rest of the country.