Based on the latest Bureau of Labor Statistics OEWS data — updated August 12, 2026.
| Missouri | National | Difference | |
|---|---|---|---|
| Median annual salary | $135,130 | $140,258 | -4% |
| Median hourly wage | $64.97 | $67.43 | -4% |
Adjusted for local price levels (100 = national average), the cost-adjusted median is $148,822.
| City | Median | Entry Level | Experienced | Cost of Living |
|---|---|---|---|---|
| City-level data coming soon. | ||||
The median annual salary for a Physician Assistant in Missouri is $135,130, or about $64.97 per hour, according to BLS OEWS data.
The national median for Physician Assistants is $140,258. Missouri is -4% below the national median.
Entry-level physician assistants in Missouri typically earn from varies by experience depending on the city and employer.
With 2,300 physician assistant jobs on record and a median salary of $135,130, Missouri offers competitive pay compared to the rest of the country.